Annals of Applied Physiology

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RS V. Diagnostic Accuracy of Rapid 13c Urea Breath Test Compared To HpSA Test to Manage Helicobacter Pylori Induced Peptic Ulcer. ANN. APPL. PHYSIOL. 2024; 1 : 26
URL: http://aapjournal.com/article-1-26-en.html

Background. A definitive diagnosis of H pylori infection will ensure better treatment outcomes in today's world. In this regard, breath tests and stool tests are extensively used. Hardly few studies have been done to establish their better diagnostic accuracy.
Objectives. Hence, this study was undertaken to compare urea breath and stool antigen tests for their accuracy in identifying H pylori infection.
Methods. One hundred thirty-nine abdominal pain patients who were diagnosed with rapid urease test underwent stool antigen testing and urea breath test.
Results. Based on the rapid urease test, for Urea Breath Test Sensitivity, specificity, positive predictive values, negative predictive values, and Accuracy were76% 34%, 60%, 52%, and 58%, and by the HpSA Test Sensitivity, specificity, positive predictive values, negative predictive values and Accuracy were75%, 33%, 60%, 49%, and 57%. There were no significant differences in the performance of these tests.
Conclusions. Urea Breath and HpSA Tests have the same diagnostic accuracy in H. Pylori Infection.